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SR-1114 Catalog No.:M33701-C exhibits LD50 and ED50 values

SKU: 31167931418

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Description

exhibits LD50 and ED50 values of 142 mg and 7

InChi: InChI=1S/C21H28N6O4S/c1-4-6-16-18-19(26(3)25-16)21(28)24-20(23-18)15-13-14(7-8-17(15)31-5-2)32(29

InChi: InChI=1S/C6H12N6S2

PNT1B healthy human prostate cell proliferation is not inhibited

SR-1114 Catalog No.:M33701-C exhibits LD50 and ED50 valuesSR 1114 is a first in class PROTAC ENL degrader. SR 1114 elicits rapid, CRBN dependent degradation of ENL with DC50s of 150 nM, 311 nM, and 1. 65 M in MV4; 11 , MOLM 13, and OCI AML 2 cells, respectively. Product information CAS Number: 2769141 82 2 Molecular Weight: 830. 86 Formula: C39H42N8O11S Smiles: O=S(=O)(NC1=CC=CC(=C1)C1=CN2C=C(C=CC2=N1)C(=O)NC1CCC1)NCCOCCOCCNC(=O)COC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O InChiKey: WPVVPCVQEBQVLL UHFFFAOYSA N

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