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(2009) Cell Stem Cell
InChiKey: XXRVYAFBUDSLJX-UHFFFAOYSA-N
Epub 2013 Apr 11
VR23: A Quinoline-Sulfonyl Hybrid Proteasome Inhibitor That Selectively Kills Cancer via Cyclin E-Mediated Centrosome Amplification
PKC-IN-1 - CAS# 1046787-18-1 size:10mg solid (2009) Cell Stem CellPKC IN 1, CAS No. 1046787 18 1, is a potent, ATP competitive and reversible inhibitor of conventional PKC enzymes with Kis of 5. 3 and 10. 4 nM for human PKC and PKC, and IC50s of 2. 3, 8. 1, 7. 6, 25. 6, 57. 5, 314, 808 nM for PKC, PKCI, PKCII, PKC, PKC, PKC mu and PKC, respectively. IC50: 2. 3 nM (Human PKC), 7. 6 nM (Human PKCII), 8. 1 nM (Human PKCI), 25. 6 nM (Human PKC), 57. 5 nM (Human PKC), 314 nM (Human PKC mu), 808 nM (Human PKC) Ki: 5. 3 nM
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