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JUN90152 shows 150-fold selectivity for SMS2 over SMS1 (IC50 of 1000 nM)
2016 Oct 10
Solubility: DMSO: 100 mg/mL(118
2020 Jul 9
Avatrombopag Catalog No.:M11396-10 JUN90152 shows 150-fold selectivity forAvatrombopag, also known as AKR 501, YM477, AS 1670542 or E5501, is a novel orally active thrombopoietin (TPO) receptor agonist. AKR 501 specifically targeted the TPO receptor and stimulated megakaryocytopoiesis throughout the development and maturation of megakaryocytes just as rhTPO did. AKR 501 may be useful in the treatment of patients with thrombocytopenia. Avatrombopag was first approved in 2018. Product information CAS Number: 570406 98 3
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