![SPD304 dihydrochloride tractylenolide III Smiles: N[C@H]1[C@@H](CC[C@@H](OC(=O)N2CCC(CC2)N2C3=CC=CN=C3NC2=O)C2=NC=CC=C21)C1=CC=CC(F)=C1F](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M12836_1626934481.gif?v=1628139727)
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Smiles: N[C@H]1[C@@H](CC[C@@H](OC(=O)N2CCC(CC2)N2C3=CC=CN=C3NC2=O)C2=NC=CC=C21)C1=CC=CC(F)=C1F
suggesting the involvement of histone H3 lysine 9 (H3K9) methyltransferase G9a in the maintenance of HIV-1 latency
1 h in dog
5-dimethyl-4-[(4-methyl-1-piperazinyl)carbonyl]-1H-pyrrol-2-yl]methylene]-2
SPD304 dihydrochloride tractylenolide III Smiles: N[C@H]1[C@@H](CC[C@@H](OC(=O)N2CCC(CC2)N2C3=CC=CN=C3NC2=O)C2=NC=CC=C21)C1=CC=CC(F)=C1FSPD304 dihydrochloride is a selective TNF inhibitor, which promotes dissociation of TNF trimers and therefore blocks the interaction of TNF and its receptor. SPD304 has an IC50 of 22 M for inhibiting in vitro TNF receptor 1 (TNFR1) binding to TNF . Product information CAS Number: 1049741 03 8 Molecular Weight: 620. 53 Formula: C32H34Cl2F3N3O2 Chemical Name: 6, 7 dimethyl 3 {[methyl({2 [methyl({1 [3 (trifluoromethyl)phenyl] 1H indol 3