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Cladribine - CAS# 4291-63-8 lbutyric acid (4-PBA) Curr Drug Discov Technol

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Description

Curr Drug Discov Technol

Vesnarinone inhibits angiogenesis and tumorigenicity of human oral squamous cell carcinoma cells by suppressing the expression of vascular endothelial growth factor and interleukin-8

Chemical Name: 1-[(1S

grapefruits

Cladribine - CAS# 4291-63-8 lbutyric acid (4-PBA) Curr Drug Discov TechnolCladribine is a purine nucleoside antimetabolite analogue. Cladribine triphosphate, a phosphorylated metabolite of cladribine, incorporates into DNA, resulting in single strand breaks in DNA, depletion of nicotinamide adenine dinucleotide (NAD) and adenosine triphosphate (ATP), and apoptosis. Because this agent is resistant to adenosine deaminase, an enzyme that inactivates some antineoplastic agents, it is selectively toxic to lymphocytes and

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