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Verteporfin (Visudyne) - YAP Inhibitor. CAS# 129497-78-5 045 IDO5L and IDO-IN-2 with CAS#914471-09-3

SKU: 35134362940

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Description

IDO5L and IDO-IN-2 with CAS#914471-09-3

and caspase-9 and poly (ADP) ribosome polymerase

The doubling time of W3110RL is 40 min in the presence of 1 μg/mL CHIR-090

Solubility: DMSO up to 100mM

Verteporfin (Visudyne) - YAP Inhibitor. CAS# 129497-78-5 045 IDO5L and IDO-IN-2 with CAS#914471-09-3Verteporfin (Visudyne), CAS No. 129497 78 5, is a potent and selective YAP inhibitor, disrupts YAP TEAD interactions and enhances trypsin cleavage of YAP with EC50 ~100 nM. It inhibits growth and proliferation of retinoblastoma cells. It also significantly blocks cancer stem cell (CSC) properties in cells with high YAP1 and a high proportion of ALDH1(+). In vivo it can suppress YAP induced liver overgrowth in mice. Product information CAS Number:

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