PF 05089771 tosylate - CAS# 1430806-04-4 0764 Smiles: CC1=CC=CN2C(=O)C(/C=C(\C#N)/C3=NC4=CC=CC=C4S3)=C(N=C21)OC1C=CC(F)=CC=1

Smiles: CC1=CC=CN2C(=O)C(/C=C(\C#N)/C3=NC4=CC=CC=C4S3)=C(N=C21)OC1C=CC(F)=CC=1

000 nM in WIF-B9 hepatocytes

InChi: InChI=1S/C16H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h2-15H2

18% and 21

PF 05089771 tosylate - CAS# 1430806-04-4 0764 Smiles: CC1=CC=CN2C(=O)C(/C=C(\C#N)/C3=NC4=CC=CC=C4S3)=C(N=C21)OC1C=CC(F)=CC=1PF 05089771 tosylate is a potent, orally active and selective arylsulfonamide Nav1. 7 inhibitor, with IC50 values of 11 nM, 12 nM, 13 nM, 171 nM and 8 nM for hNav1. 7, cynNav1. 7, dogNav1. 7, ratNav1. 7, and musNav1. 7, respectively. PF 05089771 is under the study for pain and diabetic neuropathy. Product information CAS Number: 1430806 04 4 Molecular Weight: 672. 56 Formula: C25H20Cl2FN5O6S3 Chemical Name: 4 [2 (5 amino 1H pyrazol 4 yl) 4