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MGL-3196 - CAS# 920509-32-6 PTO-253 In combination with CHIR99021

SKU: 35614972871

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Description

In combination with CHIR99021

): Indication: For the treatment of primary biliary cholangitis [Internet]

Swearingen D

LY2784544 significantly inhibits STAT5 phosphorylation in JAK2-V617F Ba/F3 xenografts with a Threshold Effective Dose 50 (TED50) of 12

MGL-3196 - CAS# 920509-32-6 PTO-253 In combination with CHIR99021MGL 3196, CAS No. 920509 32 6, also known as Resmetirom, is a potent and highly selective thyroid hormone receptor agonist in clinical trials for the treatment of dyslipidemia. The beneficial effects of thyroid hormone (TH) on lipid levels are primarily due to its action at the thyroid hormone receptor (THR ) in the liver, while adverse effects, including cardiac effects, are mediated by thyroid hormone receptor (THR ). Product information CAS Number:

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