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LXR-623 epridil HCl CAS Number: 364622-82-2

SKU: 36253156585

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Description

CAS Number: 364622-82-2

PubMed Central PMCID: PMC3771970

Magnusson B

Transcriptional regulation of NHE3 and SGLT1 by the circadian clock protein Per1 in proximal tubule cells

LXR-623 epridil HCl CAS Number: 364622-82-2LXR623, also known as WAY 252623, is a highly selective and orally bioavailable synthetic modulator of LXR, which demonstrated efficacy for reducing lesion progression in the murine LDLR( ) atherosclerosis model with no associated increase in hepatic lipogenesis either in this model or Syrian hamsters. In nonhuman primates with normal lipid levels, WAY 252623 significantly reduced total (50 55%) and LDL cholesterol (LDLc) (70 77%) in a time and dose

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