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Tiotropium (bromide hydrate) 383 ONT-093 could inhibit P-gp and

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Description

ONT-093 could inhibit P-gp and reverse multidrug resistance at nM concentrations with no effect on paclitaxel pharmacokinetics

20(11):1399-410

4-5-17)23-8-12(7-21-23)14-13-3-6-18-15(13)20-11-19-14/h3

5-Difluorophenyl)acetyl]-L-alanyl-2-phenylglycine-1

Tiotropium (bromide hydrate) 383 ONT-093 could inhibit P-gp andTiotropium Bromide hydrate (BA 679BR) is a monohydrate of tiotropium bromide (Spiriva; Tiova; BA 679BR; tiopropium) that is an anticholinergic and bronchodilator and a muscarinic receptor antagonist. Product information CAS Number: 139404 48 1 Molecular Weight: 490. 43 Formula: C19H24BrNO5S2 Synonym: Spiriva Chemical Name: (1R,2R,4S,5S) 7 {[2 hydroxy 2,2 bis(thiophen 2 yl)acetyl]oxy} 9,9 dimethyl 3 oxa 9 azatricyclo[3. 3. 1. 0,]nonan 9 ium hydrate

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