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AG14361 induces caspase 3/7 activation and cell cycle abnormalities
1 mg/kg) has excellent PK characteristics with 76% bioavailability
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4-benzotriazin-7-yl]phenyl benzoate hydrochloride
Phenformin Hydrochloride Catalog No.:M11294-10 AG14361 induces caspase 3/7 activationPhenformin Hydrochloride is the hydrochloride salt form of phenformin, an agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity. It is potent to lower blood glucose concentrations in patients with non insulin dependent diabetes mellitus. Phenformin Hydrochloride improves insulin sensitivity and decrease insulin resistance by inhibiting complex 1 of the mitochondrial respiratory chain and inducing AMP activated protein