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resistant strains
InChiKey: YDDUMTOHNYZQPO-RVXRWRFUSA-N
) significantly shrinks the tumors by day 25
Formula: C10H17BrF3NO3
PS210 oleoyl-sn-glycerol resistant strainsPS210 is a potent and selective PDK1 activator with a Kd of 3 M and targets the PIF binding pocket of PDK1. PS210 is inactive against other protein kinases, including PDK1 downstream signaling components such as S6K, PKB Akt or GSK3. In cells, the prodrug of PS210 (PS423) acts as a substrate selective inhibitor of PDK1, inhibiting the phosphorylation and activation of S6K. Product information CAS Number: 1221962 86 2 Molecular Weight: 380. 31 Formula:
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