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4 nM for PARP1 in a cell-free assay
The maximal increase in the number of erections (60%) is detected at 5 mg/kg but was not significantly different from that produced by 1 mg/kg
CNV-1014802
GNE-049 is further evaluated in a rat single dose (30-250 mg/kg QD) toxicokinetic study
O-1821 Catalog No.:M22754-C 4 nM for PARP1 inO 1821 is an cannabidiol analog with similar structure to O 1918, a selective antagonist of abnormal cannabidiol. Abnormal cannabidiol, a synthetic regioisomer of cannabidiol, fails to elicit either central cannabinoid (CB1) or peripheral cannabinoid (CB2) receptors and is lack of psychotropic activity. It can induce endothelium dependent vasodilation through a CB1 CB2 nitric oxide independent mechanism. In vitro: O 1821 is a cannabidiol analog with
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