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Epub 2007 Oct 5
indicating that NHC-TP competes predominantly with CTP for incorporation
Smiles: NC(=O)C1C=CC(=CC=1)C1C=NN2C=CC(NCC3=CN=CC=C3)=NC2=1
Formula: C26H21F2N5O3
W-54011 Catalog No.:M20237-C Epub 2007 Oct 5W 54011 is a potent and orally active non peptide C5a receptor antagonist. W 54011 inhibits the binding of 125I labeled C5a to human neutrophils with a Ki value of 2. 2 nM. W 54011 also inhibits C5a induced intracellular Ca2+ mobilization, chemotaxis, and generation of ROS in human neutrophils with IC50s of 3. 1 nM, 2. 7 nM, and 1. 6 nM, respectively. Product information CAS Number: 405098 33 1 Molecular Weight: 493. 08 Formula: C30H37ClN2O2 Chemical
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