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PMID: 32154864
50(10):1077-82
PF-4708671 specifically inhibits the S6K1 isoform with a Ki of 20 nM and IC50 of 160 nM
ClH/c1-20-17-9-7-12(13-4-2-3-5-14(13)17)11-6-8-15(18)16(19)10-11
Toceranib phosphate ties PMID: 32154864Toceranib, also known as PHA 291639 and SU 11654, is a receptor tyrosine kinase inhibitor and is used in the treatment of canine mast cell tumor also called mastocytoma. Toceranib phosphate was approved for dog. Toceranib is likely to act mostly through inhibition of the kit tyrosine kinase, though it may also have an anti angiogenic effect. Product information CAS Number: 874819 74 6 Molecular Weight: 494. 45 Formula: C22H28FN4O6P Chemical Name: 5
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