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OPC-14523 hydrochloride ent (6-22) amide TFA 25(12):1883-90

SKU: 40421470800

4.7
USD100.00 USD146.00

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Description

25(12):1883-90

Smiles: CC(C)(C)C1=CC(O)=CC=C1O

InChi: InChI=1S/C24H23FN4OS/c1-15-13-29(14-26-15)20-11-10-18(12-21(20)30-2)27-24-28-23-19(4-3-5-22(23)31-24)16-6-8-17(25)9-7-16/h6-14

InChi: InChI=1S/C20H18N6O/c21-16(10-14-12-24-17-4-2-1-3-15(14)17)20(27)26-25-11-13-5-6-18-19(9-13)23-8-7-22-18/h1-9

OPC-14523 hydrochloride ent (6-22) amide TFA 25(12):1883-90OPC 14523 hydrochloride is an orally active sigma and 5 HT1A receptor agonist, with high affinity for sigma receptors (1 2 IC50=47 56 nM), the 5 HT1A receptor (IC50=2. 3 nM), and the 5 HT transporter (IC50=80 nM). OPC 14523 hydrochloride shows antidepressant like activity. Product information CAS Number: 145969 31 9 Molecular Weight: 450. 40 Formula: C23H29Cl2N3O2 Chemical Name: 1 {3 [4 (3 chlorophenyl)piperazin 1 yl]propyl} 5 methoxy 1,2,3,4

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