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5-Hydroxyferulic acid is a precursor in the biosynthesis of sinapic acid and is also a COMT non-esterifed substrate
followed by apoptosis
but only activatedRARβ and RARγ with about 10% efficacy at the highest dose (1000 nM) tested
with a tendency to elevated concentration in patients with chronic periodontitis
Polygalacic acid 7781 5-Hydroxyferulic acid is a precursorPolygalacic acid, is a triterpene, isolated from the root of Polygala tenuifolia Willd. Polygalacic acid inhibits MMP expression. Polygalacic acid may have a therapeutic effect in Osteoarthritis (OA) treatment . Polygalacic acid exerts a significant neuroprotective effect on cognitive impairment, PA improves cholinergic system reactivity by inhibiting acetylcholinesterase (AChE) activity, increasing choline acetyltransferase (ChAT) activity, and