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In the HCT116 human colon cancer xenograft model
histologic type
CAS Number: 544467-07-4
1-Naphthylacetyl spermine trihydrochloride
O-Desmethyl gefitinib - CAS# 847949-49-9 182AM7 E In the HCT116 human colonO Desmethyl gefitinib is an active metabolite of Gefitinib in human plasma. The formation of O desmethyl gefitinib is dependent on CYP2D6 activity. O desmethyl gefitinib inhibits EGFR with an IC50 of 36 nM in subcellular assays. Product information CAS Number: 847949 49 9 Molecular Weight: 432. 88 Formula: C21H22ClFN4O3 Chemical Name: 4 [(3 chloro 4 fluorophenyl)amino] 6 [3 (morpholin 4 yl)propoxy]quinazolin 7 ol Smiles:
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