15a-Hydroxy-3, 11, 23-trioxo-lanost-8, 20-dien-26-oic acid Catalog No.:M16769-C GSKJ1 is a selective and

GSKJ1 is a selective and potent histone demethylase inhibitor (GSK-J1) that has significant activity (IC50 60 nM for human JmjD3) in vitro and in cells using an ester derivative (GSK-J4: 1 µM < IC50 < 10 µM

Mastrianni KR

A3 is also a competitive inhibitor of cAMP-dependent protein kinase

CC(C)(C)/[N+](/[O-])=C/C1=CC=C(C=C1S([O-])(=O)=O)S([O-])(=O)=O

15a-Hydroxy-3, 11, 23-trioxo-lanost-8, 20-dien-26-oic acid Catalog No.:M16769-C GSKJ1 is a selective and15a Hydroxy 3,11,23 trioxo lanost 8,20 dien 26 oic acid, a Lanostane triterpenoid, possesses NO production inhibitory activities of LPS induced microglia. Product information CAS Number: 1961358 01 9 Molecular Weight: 498. 65 Formula: C30H42O6 Chemical Name: (5Z) 6 [(1R, 3S, 3aR, 5aR, 9aS, 11aR) 3 hydroxy 3a, 6, 6, 9a, 11a pentamethyl 7, 10 dioxo 1H, 2H, 3H, 3aH, 4H, 5H, 5aH, 6H, 7H, 8H, 9H, 9aH, 10H, 11H, 11aH cyclopenta[a]phenanthren 1 yl] 2 methyl