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which inhibits ATR immunoprecipitated from HeLa nuclear extracts with an IC50 of 5 nM and ATR mediated phosphorylation of Chk1 in HT29 colorectal adenocarcinoma tumor cells with an IC50 of 50 nM
In order to examine the role of PKC in p38MAPK phosphorylation
PubMed PMID: 18791063
Suchankova T
GW9508 - selective FFA1 GPR40 agonist. CAS# 885101-89-3 P50469 which inhibits ATR immunoprecipitated fromGW9508 is a potent and selective agonist for FFA1 (GPR40) with pEC50 of 7. 32, 100 fold selective against GPR120, stimulates insulin secretion in a glucose sensitive manner. Product information CAS Number: 885101 89 3 Molecular Weight: 347. 41 Formula: C22H21NO3 Chemical Name: 3 (4 ((3 phenoxybenzyl)amino)phenyl)propanoic acid Smiles: OC(=O)CCC1C=CC(=CC=1)NCC1=CC(=CC=C1)OC1C=CC=CC=1 InChiKey: DGENZVKCTGIDRZ UHFFFAOYSA N InChi: InChI=1S C22H21NO3 c24
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