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Because of passive accumulation within tumors
[Epub ahead of print] PubMed PMID: 27444277
Smiles: CN(CCCNC1=NC(NC2C=CC(=CC=2)OCCCOCCCCOCCCOCC(=O)N[C@H](C(=O)N2C[C@@H](O)C[C@H]2C(=O)NCC2C=CC(=CC=2)C2SC=NC=2C)C(C)(C)C)=NC=C1Br)C(=O)C1CCC1
19(19):5576-81
Amisulpride Hydrochloride one B Because of passive accumulation withinAmisulpride is an atypical antipsychotic used to treat psychosis in schizophrenia and episodes of mania in bipolar disorder. In Italy, it is also used as a treatment for dysthymia. It was introduced by Sanofi Aventis in the 1990s. Its patent had expired by 2008 and hence generic formulations are now available. Amisulpride function primarily as a D2 and D3 receptor antagonist. It has high affinity for these receptors with dissociation constants of 2. 2
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