Propargyl-PEG4-acid Size:Contact [email protected] for quotation CC1C2=C(SC=1C(=O)NCCCCCNC1=CC=CC3=C1C(=O)N(C1CCC(=O)NC1=O)C3=O)N1C(=NN=C1C)[C@H](CC(=O)OC)N=C2C1C=CC(Cl)=CC=1

CC1C2=C(SC=1C(=O)NCCCCCNC1=CC=CC3=C1C(=O)N(C1CCC(=O)NC1=O)C3=O)N1C(=NN=C1C)[C@H](CC(=O)OC)N=C2C1C=CC(Cl)=CC=1

Smiles: COC1C=C(CCC(=O)CC(=O)CCC2C=C(OC)C(O)=CC=2)C=CC=1O

InChi: InChI=1S/C20H22O7/c1-9-8-14(11(3)17(21)15(9)19(22)23)27-20(24)16-10(2)7-13(25-5)12(4)18(16)26-6/h7-8

Smiles: COC1=CC=C(C[C@H]2COC(=O)[C@@H]2CC2=CC(OC)=C(C=C2)O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)C=C1OC

Propargyl-PEG4-acid Size:Contact [email protected] for quotation CC1C2=C(SC=1C(=O)NCCCCCNC1=CC=CC3=C1C(=O)N(C1CCC(=O)NC1=O)C3=O)N1C(=NN=C1C)[C@H](CC(=O)OC)N=C2C1C=CC(Cl)=CC=1Propargyl PEG4 acid is a PEG based PROTAC linker can be used in the synthesis of BTK IAP PROTACs Ibrutinib (HY 10997) based PROTAC 2 and an analogue PROTAC 3. PROTAC 3 causes BTK degradation with a DC50 of 200 nM in THP 1 cells. Product information CAS Number: 1415800 32 6 Molecular Weight: 260. 28 Formula: C12H20O6 Chemical Name: 4,7,10,13 tetraoxahexadec 15 ynoic acid Smiles: C#CCOCCOCCOCCOCCC(O)=O InChiKey: WMBXAUWIPBFEOK UHFFFAOYSA N InChi: