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L-Canaline Catalog No.:M18885-C Deschloroclozapine displays low 'off-target' receptor

SKU: 43483032387

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Description

Deschloroclozapine displays low 'off-target' receptor binding and rapid binding and activation of hM3Dq and hM4Di in mice and non-human primates

perfused LCB 2853 decreases the weight of thrombi in a dose related manner with ED50 of 220 μg/kg/min

MC3R and MC5R with IC50s of 2067

PMCID: PMC6344135

L-Canaline Catalog No.:M18885-C Deschloroclozapine displays low 'off-target' receptorL Canaline is a nonprotein amino acid stored in many leguminous plants. L Canaline is a cytotoxic metabolite catalyzed by L canavanine and its arginase. L Canaline is a potent and irreversible inhibitor of ornithine aminotransferase. L Canaline inhibits the growth of the malaria parasite Plasmodium falciparum with an IC50 of 297 nM. L Canaline has anticancer and antiproliferative effects. Product information CAS Number: 496 93 5 Molecular Weight: 134.

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