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which inhibits RANKL-induced osteoclast formation and bone resorption in vitro and prevents LPS-induced bone loss in vivo
40(1):13-22
25)/b21-20+
Formula: C15H20O7
TIK-301 Catalog No.:M27860-C which inhibits RANKL-induced osteoclast formationTIK 301 (PD 6735) is a chlorinated melatonin derivative and a potent, high affinity and orally active melatonin MT1 and MT2 receptors agonist with Kis of 0. 081 nM and 0. 042 nM, respectively. TIK 301 is also a 5 HT2B 5 HT2C receptors antagonist with antidepressant action. TIK 301 has the potential for sleep disorders and other circadian rhythm disorders treatment. Product information CAS Number: 118702 11 7 Molecular Weight: 280. 75 Formula:
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