PI3Kdelta inhibitor 1 ro-2-(4-methoxyphenyl)-4-oxo-1 5-benzothiazepin-5(2H)-yl]ethyl]methyl-d3-carbamic Acid 1-Chloroethyl Ester ¹⁸]icosa-1(12)

¹⁸]icosa-1(12)

Chemical Name: (Z)-N-(2-{2-[(dipropylamino)methyl]piperidin-1-yl}ethyl)-10-hydroxy-2

1 μM and for a shorter time also shows a drop in Lys9 methylation

highly selective and potent covalent interleukin-2-inducible T-cell kinase (ITK) and resting lymphocyte kinase (RLK) dual inhibitor with IC50s of 0

PI3Kdelta inhibitor 1 ro-2-(4-methoxyphenyl)-4-oxo-1 5-benzothiazepin-5(2H)-yl]ethyl]methyl-d3-carbamic Acid 1-Chloroethyl Ester ¹⁸]icosa-1(12)PI3Kdelta inhibitor 1 (Compound 5d) is a potent, selective and orally available PI3K inhibitor with an IC50 of 1. 3 nM. Product information CAS Number: 2242109 74 4 Molecular Weight: 558. 69 Formula: C27H38N6O5S Chemical Name: N [2 methoxy 5 (1 methyl 4 {[(3R) 1 [2 (oxan 4 yl)ethyl]piperidin 3 yl]methoxy} 1H pyrazolo[3,4 b]pyridin 6 yl)pyridin 3 yl]methanesulfonamide Smiles: CN1N=CC2=C1N=C(C=C2OC[C@H]1CN(CCC1)CCC1CCOCC1)C1C=C(NS(C)(=O)=O)C(=NC=1)OC