Malic enzyme inhibitor ME1 Htracer 6-²H₁₁)cyclohexyl]-2-hydroxy-2-phenylacetate hydrochloride

6-²H₁₁)cyclohexyl]-2-hydroxy-2-phenylacetate hydrochloride

7 and 17 nM in the absence and presence of 10% serum

64 nM at CB2 vs 270 nM at the psychoactive CB1 receptor

4 nM and effectively blocks Ca2+ flux with an IC50 of 0

Malic enzyme inhibitor ME1 Htracer 6-²H₁₁)cyclohexyl]-2-hydroxy-2-phenylacetate hydrochlorideMalic enzyme inhibitor ME1 (ME1; compound 1) is a potent inhibitor of Malic enzyme (ME1) with an IC50 of 0. 15 M. Product information CAS Number: 522649 59 8 Molecular Weight: 351. 40 Formula: C20H21N3O3 Chemical Name: 3 [4 (4 hydroxyphenyl)piperazin 1 yl] 1 phenylpyrrolidine 2,5 dione Smiles: OC1C=CC(=CC=1)N1CCN(CC1)C1CC(=O)N(C2C=CC=CC=2)C1=O InChiKey: JJFJQFJFFVLMCX UHFFFAOYSA N InChi: InChI=1S C20H21N3O3 c24 17 8 6 15(7 9 17)21 10 12 22(13 11 21)18