Synta66 trazuril C2HF3O2/c1-24(62)39-46(75)58-28(6-3-4-15-49)43(72)56-29(12-13-38(67)68)41(70)52-21-37(66)55-33(48(77)78)23-81-80-22-27(50)40(69)59-32(19-35(51)64)47(76)61-16-5-7-34(61)45(74)57-30(14-17-79-2)42(71)53-20-36(65)54-31(44(73)60-39)18-25-8-10-26(63)11-9-25

C2HF3O2/c1-24(62)39-46(75)58-28(6-3-4-15-49)43(72)56-29(12-13-38(67)68)41(70)52-21-37(66)55-33(48(77)78)23-81-80-22-27(50)40(69)59-32(19-35(51)64)47(76)61-16-5-7-34(61)45(74)57-30(14-17-79-2)42(71)53-20-36(65)54-31(44(73)60-39)18-25-8-10-26(63)11-9-25

AA92593 was used at 10 µM final concentration in various in vitro assays

Solubility: DMSO : 20 mg/mL (47

Noncompartmental pharmacokinetic analysis indicates ML218 (1 mg/kg

Synta66 trazuril C2HF3O2/c1-24(62)39-46(75)58-28(6-3-4-15-49)43(72)56-29(12-13-38(67)68)41(70)52-21-37(66)55-33(48(77)78)23-81-80-22-27(50)40(69)59-32(19-35(51)64)47(76)61-16-5-7-34(61)45(74)57-30(14-17-79-2)42(71)53-20-36(65)54-31(44(73)60-39)18-25-8-10-26(63)11-9-25Synta66 is an inhibitor of store operated calcium entry channel Orai, which forms the pore of the CRAC channel, and used for the research of neurological disease. Product information CAS Number: 835904 51 3 Molecular Weight: 352. 36 Formula: C20H17FN2O3 Chemical Name: N {2',5' dimethoxy [1,1' biphenyl] 4 yl} 3 fluoropyridine 4 carboxamide Smiles: COC1C=C(C(=CC=1)OC)C1C=CC(=CC=1)NC(=O)C1C=CN=CC=1F InChiKey: GFEIWXNLDKUWIK UHFFFAOYSA N InChi: InChI=1S