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Formula: C26H23F2N3O4
It acts as an antioxidant according to in vitro studies
also known as gold thioglucose and Solganal
CAS Number: 912445-05-7
AZD-5438 702 Formula: C26H23F2N3O4AZD5438 is a potent inhibitor of cyclin dependent kinase (cdk) 1, 2, and 9 (IC(50), 16, 6, and 20 nmol L, respectively). In vitro, AZD5438 showed significant antiproliferative activity in human tumor cell lines (IC(50) range, 0. 2 1. 7 micromol L), causing inhibition of the phosphorylation of cdk substrates pRb, nucleolin, protein phosphatase 1a, and RNA polymerase II COOH terminal domain and blocking cell cycling at G(2) M, S, and G(1) phases.
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