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Prinaberel shows a marked reduction in the expression of inflammation regulatory proteins such as p-NFκBp65
Formula: C21H22O11
MIC50 and MIC90 are 1 and 2 mg/L for Acinetobacter baumannii (A
InChi: InChI=1S/C53H67FN8O8S/c1-33-46(71-32-57-33)34-11-12-35(27-56-48(64)42-26-37(63)29-62(42)50(66)47(52(2
N-Desethyl Sunitinib Size:Solid 10 mg Prinaberel shows a marked reductionN Desethyl Sunitinib is a metabolite of sunitinib. Sunitinib is a potent, ATP competitive VEGFR, PDGFR and KIT inhibitor with Ki values of 2, 9, 17, 8 and 4 nM for VEGFR 1, 2, 3, PDGFR and KIT, respectively. Sunitinib also potently inhibits Kit and FLT 3. Sunitinib inhibits VEGF induced proliferation of serum starved HUVECs with IC50 of 40 nM, and inhibits PDGF induced proliferation of NIH 3T3 cells overexpressing PDGFR or PDGFR with IC50 of 39 nM and
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