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Consistent with the effects on thermogenic and β-oxidation gene expression and body weights
Hedgehog inhibitor PF-04449913 appears to inhibit Hh pathway signaling
InChiKey: DGCPIBPDYFLAAX-YTAGXALCSA-N
33(1):39-60
Y 11 Size:Contact [email protected] for quotation Consistent with the effects onFocal adhesion kinases (FAKs) are non receptor tyrosine kinases that play roles in regulating diverse processes, including cell adhesion, spreading, migration, proliferation, and apoptosis. They are over expressed in many types of cancer. Y11 inhibits FAK1 autophosphorylation by blocking phosphorylation of Y397. At 100 M, it was shown to decrease cell viability of T47D breast cancer and C8161 melanoma cell lines. Product information CAS Number: