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Molecular Weight: 305
Cell Mol Biol Lett
106(8):1386-94
LY2784544 significantly inhibits STAT5 phosphorylation in JAK2-V617F Ba/F3 xenografts
EX-527 - SIRT1 Inhibitor. CAS# 49843-98-3 60071 Molecular Weight: 305EX 527, CAS No. 49843 98 3, is a highly potent and selective inhibitor of SIRT1 with an IC50 ~98 nM. It does not inhibit histone deacetylase (HDAC) or other sirtuin deacetylase family members (IC50 ~20 100 M). EX 527 has been used to investigate the relationship between SIRT1 mediated deacetylation of p53, p53 activity, and cell survival following DNA damage, as well as many other biological processes involving SIRT1. Product information CAS Number:
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