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Tie2 kinase inhibitor 5
1H3/b11-4+
PI-828 is a dual PI3K and casein kinase 2 (CK2) inhibitor with IC50s of 173 nM
Bhattacharyya S
AMG-548 dihydrochloride Size:2mg solid Tie2 kinase inhibitor 5AMG 548 dihydrochloride, an orally active and selective p38 inhibitor (Ki=0. 5 nM), shows slightly selective over p38 (Ki=36 nM) and >1000 fold selective against p38 and p38. AMG 548 dihydrochloride is also extremely potent in the inhibition of whole blood LPS stimulated TNF (IC50=3 nM). AMG 548 dihydrochloride inhibits Wnt signaling by directly inhibiting Casein kinase 1 isoforms and . Product information Molecular Weight: 534. 48 Formula: