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It is used to treat a variety of cardiac arrhythmias including paroxysmal atrial fibrillation (episodic irregular heartbeat originating in the upper chamber of the heart)
extracted from patent US20170008904A1
 2018 Nov
It is one of the treatments of choice for Prinzmetal angina
AP14145 hydrochloride Size:Contact [email protected] for quotation It is used to treatAP14145 hydrochloride is a potent KCa2 (SK) channel negative allosteric modulator with an IC50 of 1. 1 M for KCa2. 2 (SK2) and KCa2. 3 (SK3) channels. AP14145 hydrochloride inhibition strongly depends on two amino acids, S508 and A533 in the channel. AP14145 hydrochloride prolonged atrial effective refractory period (AERP) in rats and demonstrates antiarrhythmic effects in a Vernakalant resistant porcine model of atrial fibrillation (AF). Product