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Saracatinib - CAS# 379231-04-6 Catalog No.:M7189-2 As a tool compound

SKU: 48361053366

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Description

As a tool compound

At this time point

DASA-58 (40 μM) treated cells are injected into male SCID-bg/bg mice bearing PC3 tumors by IV

Epub 2011 Sep 22

Saracatinib - CAS# 379231-04-6 Catalog No.:M7189-2 As a tool compoundSaracatinib, CAS No. 379231 04 6, also known as AZD0530, is an orally available dual specific inhibitor of Src and Abl with anti invasive and anti tumor activities. Src and Abl are protein tyrosine kinases that are overexpressed in chronic myeloid leukemia cells. Saracatinib binds to and inhibits these tyrosine kinases and their effects on cell motility, cell migration, adhesion, invasion, proliferation, differentiation, and survival. Product

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