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2-fold higher than the values for dolastatin 10
3R)-1-(acetyloxy)-3-[(2S
at hydroxylation sites in the oxygen-dependent degradation domain (ODDD)
Compound X
BYK 191023 dihydrochloride Catalog No.:M22335-C 2-fold higher than the valuesIC50: 86 nM for iNOS NO synthases are enzymes responsible for the generation of nitric oxide from the amino acid L arginine. Once expressed the inducible NO synthase (iNOS) is active and produces M concentrations of NO over longer periods. The iNOS expression is stimulated in various cells by proinflammatory signals and is involved in immune defense. BYK191023 is a selective inhibitor of the inducible nitric oxide synthase (NOS). In vitro: BYK191023
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