![NVP-BGJ398 phosphate Catalog No.:M9579-10 4S)-4-fluoro-1-(2-{[2-methyl-4-oxo-4-(pyrrolidin-1-yl)butan-2-yl]amino}acetyl)pyrrolidine-2-carbonitrile](https://cdn.shopify.com/s/files/1/0389/1897/9723/files/1689841005955.png?v=1689842438)
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4S)-4-fluoro-1-(2-{[2-methyl-4-oxo-4-(pyrrolidin-1-yl)butan-2-yl]amino}acetyl)pyrrolidine-2-carbonitrile
) significantly reduces carrageenan-induced mechanical hyperalgesia and edema formation
NSC 216666
1038/s41598-017-08711-6
NVP-BGJ398 phosphate Catalog No.:M9579-10 4S)-4-fluoro-1-(2-{[2-methyl-4-oxo-4-(pyrrolidin-1-yl)butan-2-yl]amino}acetyl)pyrrolidine-2-carbonitrileInfigratinib, also known as, BGJ398 or NVP BGJ398, is a pan FGFR kinase inhibitor, and is an orally bioavailable pan inhibitor of human fibroblast growth factor receptors (FGFRs) with potential antiangiogenic and antineoplastic activities. pan FGFR kinase inhibitor BGJ398 selectively binds to and inhibits the activities of FGFRs, which may result in the inhibition of tumor angiogenesis and tumor cell proliferation, and the induction of tumor cell
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