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InChiKey: WEIAMZKHBCLFOG-QPAIBFMUSA-N
average IC50: 1
2017024522
PIK-90 (10 mg/kg) completely protects animals from this insulin-stimulated decline in blood glucose
SB-269970 3022 InChiKey: WEIAMZKHBCLFOG-QPAIBFMUSA-NSB269970 HCl is a potent 5 HT7A antagonist (pKi = 8. 9) that demonstrates >50 fold binding selectivity over 5 HT5A and >250 fold selectivity over 5 HT1, 5 HT2, 5 HT4, 5 HT6, adrenergic 1, dopamine D2, and dopamine D3 receptors. It is also reported to block adrenergic 2 receptors in guinea pig vas deferens. SB 269970 has been used to target the 5 HT7 receptor in the study of schizophrenia like cognitive deficits. Product information CAS Number: 201038
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