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CN(C)CCCN1C2=CC=CC=C2CCC2=CC=C(Cl)C=C12
3-benzodioxole-5-carboxylate
) dose dependently lowers blood pressure in hypertensive SHRs[1]
543(7644):270-274
Duocarmycin A F265 CN(C)CCCN1C2=CC=CC=C2CCC2=CC=C(Cl)C=C12Duocarmycin A, which is one of well known antitumor antibiotics, is a DNA alkylator and efficiently alkylates adenine N3 at the 3 end of AT rich sequences in the DNA. Duocarmycin A, as a chemotherapeutic agent, results HLC 2 cells typically apoptotic changes, including chromatin condensation, sub G1 accumulation in DNA histogram pattern, and decrease in procaspase 3 and 9 levels. Product information CAS Number: 118292 34 5 Molecular Weight: 507. 49