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ClH/c1-14(15-3-5-18(22)6-4-15)26-19-9-16(17-11-25-29(2)13-17)10-20(27-19)28-21-12-23-7-8-24-21
In HEK 293 cells stably transfected with rat or human histamine H3 receptors
Pratosartan is a selective angiotensin II receptor antagonist
Smiles: CN(C)C(=O)/C=C/CNCCOC1=CC=C(C=N1)/C(=C(/CC(F)(F)F)\C1C=CC=CC=1)/C1=CC2C(C=C1)=NNC=2F
N-Desmethyl-Apalutamide tenoic acid ClH/c1-14(15-3-5-18(22)6-4-15)26-19-9-16(17-11-25-29(2)13-17)10-20(27-19)28-21-12-23-7-8-24-21N Desmethyl Apalutamide is an active metabolite of Apalutamide. N Desmethyl Apalutamide is a less potent antagonist of the androgen receptor and is responsible for one third of the activity of Apalutamide. The formation of N Desmethyl Apalutamide mediated predominantly by CYP2C8 and CYP3A4. N Desmethyl Apalutamide is moderate to strong CYP3A4 and CYP2B6 inducer and has an excellent plasma proteins bound concentration. Product information CAS Number:
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