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GSK1904529A (2 h) inhibits phosphorylation of IGF-IR and IR with IC50s of 22 and 19 nM in NIH-3T3/LISN and NIH-3T3-hIR cells
MHY1485 serves as a novel inhibitor of autophagy with an mTOR activating effect
Colivelin is an activator of STAT3
Pamabrom is a diuretic product included in retail drugs available in over-the-counter medications
Paclitaxel - CAS# 33069-62-4 Catalog No.:M11001-2 GSK1904529A (2 h) inhibits phosphorylationPaclitaxel is a compound with antineoplastic activity extracted from the Pacific yew tree Taxus brevifolia. Paclitaxel binds to tubulin and inhibits the disassembly of microtubules, thereby inhibiting cell division. This agent also induces apoptosis by binding to and blocking the function of the apoptosis inhibitor protein Bcl 2 (B cell Leukemia 2). Product information CAS Number: 33069 62 4 Molecular Weight: 853. 91 Formula: C47H51NO14 Synonym: Taxol