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PS48 - PDK1 Activator. CAS# 1180676-32-7 430 The growth of human malignant

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Description

The growth of human malignant melanoma xenografts

SKLB-610 inhibits tumor xenograft model growth of human non-smallcell lung cancer model (A549) and human colon cancer model (HCT116) and is well tolerated

MLN-9708 blocks BMSCs-induced MM cell proliferation

5 h) induces a similar level of inhibition (87±4%) of the pressor responses to angiotensin I

PS48 - PDK1 Activator. CAS# 1180676-32-7 430 The growth of human malignantPS48, CAS No. 1180676 32 7, is a novel PDK1 (phosphoinositide dependent protein kinase 1) activator (Kd = 10. 3 M), which binds to the HM PIF binding pocket rather than the ATP binding site. PS48 has been used to enhance iPSC reprogramming from human epidermal keratinocytes and endothelial cells. Product information CAS Number: 1180676 32 7 Molecular Weight: 286. 75 Formula: C17H15ClO2 Synonym: PS 48 Chemical Name: 5 (4 Chloro phenyl) 3 phenyl pent 2

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