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Formula: C13H21ClN2O
C2HF3O2/c1-8-9-27-63-89(135)114-41-19-31-70(114)86(132)101-54(6)77(123)112-68(50-118)84(130)110-66(48-56-23-11-10-12-24-56)83(129)113-69(85(131)108-64(29-14-16-39-96)90(136)117-44-22-34-73(117)91(137)115-42-20-32-71(115)87(133)103-59(76(97)122)35-36-74(120)121)51-140-139-45-37-62(80(126)109-65(46-52(2)3)81(127)105-61(30-18-40-100-93(98)99)78(124)104-60(79(125)107-63)28-13-15-38-95)106-82(128)67(49-57-25-17-26-58(94)47-57)111-88(134)72-33-21-43-116(72)92(138)75(53(4)5)102-55(7)119
spindle abnormalities and centrosome amplification
PHA665752 treatment significantly reduces the tumor growth of NCI-H69
MT-802 - CAS# 2231744-29-7 14616 Formula: C13H21ClN2OMT 802 is a potent PROTAC that induces Bruton's tyrosine kinase (BTK) knockdown. MT 802 recruits BTK to the cereblon E3 ubiquitin ligase complex to trigger BTK ubiquitination and degradation via the proteasome. MT 802 has potential for treatment of C481S mutant chronic lymphocytic leukemia (CLL). Product information CAS Number: 2231744 29 7 Molecular Weight: 787. 82 Formula: C41H41N9O8 Chemical Name: 2 [2 (2 {4 [4 amino 3 (4 phenoxyphenyl) 1H
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