N-Acetyl calicheamicin - enediyne antitumor antibiotic. CAS# 108212-76-6 Size:2mg solid Cornett EM

Cornett EM

InChiKey: PRMWGUBFXWROHD-UHFFFAOYSA-N

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4-c]pyrazol-5(2H

N-Acetyl calicheamicin - enediyne antitumor antibiotic. CAS# 108212-76-6 Size:2mg solid Cornett EMN Acetyl calicheamicin, CAS No. 108212 76 6, is a derivative of calicheamicin, and is a potent enediyne antitumor antibiotic. Calicheamicins target DNA and cause strand scission. Calicheamicins bind with DNA in the minor groove, wherein they then undergo a reaction analogous to the Bergman cyclization to generate a diradical species. This diradical, 1, 4 didehydrobenzene, then abstracts hydrogen atoms from the deoxyribose (sugar) backbone of DNA,