GSK-7975A acetic acid) PFI-4 was used at 5-10

PFI-4 was used at 5-10 µM final concentration in various in vitro assays

InChi: InChI=1S/C20H30O7/c1-10(2)5-14(22)26-12-7-19(8-21)13(6-11(12)3)27-17-15(23)16(24)18(19

Chemical Name: meso-(3R

the oral bioavailability (F) is 87% and the t1/2 is 11 h

GSK-7975A acetic acid) PFI-4 was used at 5-10GSK 7975A is a potent and orally available CRAC channel inhibitor. Product information CAS Number: 1253186 56 9 Molecular Weight: 397. 30 Formula: C18H12F5N3O2 Chemical Name: 2,6 difluoro N (1 {[4 hydroxy 2 (trifluoromethyl)phenyl]methyl} 1H pyrazol 3 yl)benzamide Smiles: OC1C=C(C(CN2C=CC(NC(=O)C3C(F)=CC=CC=3F)=N2)=CC=1)C(F)(F)F InChiKey: CPYTVBALBFSXSH UHFFFAOYSA N InChi: InChI=1S C18H12F5N3O2 c19 13 2 1 3 14(20)16(13)17(28)24 15 6 7 26(25 15)9 10 4