Pay in 4 interest-free payments of $22.50 Learn more
Ships within 48 hours · Estimated delivery Aug 11 - Aug 16
AZD-2281 selectively binds to and inhibits PARP
CAS Number: 72926-24-0
Naunyn Schmiedebergs Arch Pharmacol
7(8):e44021
AG-490 CI-006 AZD-2281 selectively binds to andTyrphostin AG490 is a JAK 2 specific inhibitor, which inhibits phosphorylation of EGFR and signal transducer and activator of transcription 3 [STAT 3], and subsequently reduce invasion and adhesion potential of malignant cells. The hematopoietic cancer c Kit+, Jak 2+ and non hematopoietic tumors c Kit+, HER 2+, JAK 2+ can be inhibited by the chemosensitizing agent AG490 causing programmed cell death. Product information CAS Number: 133550 30 8