β-Estradiol 17-valerate Catalog No.:M11088-2 is a positive allosteric modulator

is a positive allosteric modulator of mGlu5 receptors (EC50 = 33 nM)

Small-molecule correctors such as KM11060 may serve as useful pharmacological tools in studies of the F508del-CFTR processing defect and in the development of cystic fibrosis therapeutics

2014 Jul 1

5-tetrahydro-1H-3-benzazepin-2-one

β-Estradiol 17-valerate Catalog No.:M11088-2 is a positive allosteric modulatorEstradiol valerate is a synthetic ester, specifically the 17 pentanoyl ester, of the natural estrogen, 17 estradiol. It was introduced in the 1950s, and along with estradiol benzoate and estradiol cypionate, has since become one of the most widely used esters of estradiol. (Source: http: en. wikipedia. org wiki Estradiol_valerate). Product information CAS Number: 979 32 8 Molecular Weight: 356. 50 Formula: C23H32O3 Chemical Name: (1S,3aS,3bR,9bS,11aS)