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Tripathy D
Smiles: OC1CCC(CC1)NC1=NC2=C(C=N1)N=C(NC1C(F)=CC(F)=CC=1F)N2[C@@H]1COCC1
and modulates local tumour immunity by blocking the interaction between S100A9 and its ligands receptor of advanced glycation end products and Toll-like receptor 4
PubMed PMID: 25062956
Thalidomide paverine hydrochloride Tripathy DThalidomide is a synthetic derivative of glutamic acid (alpha phthalimido glutarimide) with teratogenic, immunomodulatory, anti inflammatory and anti angiogenic properties. Thalidomide acts primarily by inhibiting both the production of tumor necrosis factor alpha (TNF alpha) in stimulated peripheral monocytes and the activities of interleukins and interferons. This agent also inhibits polymorphonuclear chemotaxis and monocyte phagocytosis. In