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HTH-01-015 impaired the invasive potential of U2OS cells in a 3D cell invasion assay to the same extent as NUAK1 knockdown
E3 ligase Ligand-Linker Conjugates 32
PubMed PMID: 28724891
and cell-active dual inhibitor of PRMT4 and PRMT6 with IC50s of 34 nM and 43 nM
KB02-SLF Catalog No.:M15097-2 HTH-01-015 impaired the invasive potentialKB02 SLF is a PROTAC based nuclear FKBP12 degrader (molecular glue). KB02 SLF promotes nuclear FKBP12 degradation by covalently modifying DCAF16 (E3 ligase) and can improve the durability of protein degradation in biological systems. SLF binds ubiquitin E3 ligase ligand KB02 via a linker to form KB02 SLF. Product information CAS Number: 2384184 40 9 Molecular Weight: 949. 52 Formula: C50H65ClN4O12 Chemical Name: (1R) 1 [3 (3 {2 [2 (2 {[1 (2
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