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33-7-5-32(6-8-33)19-4-3-18(14-30-19)25(26
Chemical Name: (8R
which forms a covalent bond with Cys721 located in the ATP-binding site of Her3
6 mg/mLwarmed(24
PCNA-I1 Size:Contact [email protected] for quotation 33-7-5-32(6-8-33)19-4-3-18(14-30-19)25(26PCNA I1 is a selective inhibitor of proliferating cell nuclear antigen (PCNA, a potential anticancer target). PCNA I1 selectively binds to PCNA trimers with Kd of ~0. 2 to 0. 4 M. PCNA I1 inhibits the growth of tumor cells of various tissue types with IC50 of ~0. 2 M. PCNA I1 induces DNA damage and apoptosis in both LNCaP and PC 3 cells. PCNA I1 also induces autophagy in PC 3 cells. Product information CAS Number: 444930 42 1 Molecular Weight: 310. 37
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