FTI-2153 Catalog No.:M27128-C Smiles: [2H]C1([2H])N(CC(=O)C2=CC(C3NC(=O)C4=C(N=3)C(CCC)=NN4C)=C(C=C2)OCC)C([2H])([2H])C([2H])([2H])N(CC)C1([2H])[2H]

Smiles: [2H]C1([2H])N(CC(=O)C2=CC(C3NC(=O)C4=C(N=3)C(CCC)=NN4C)=C(C=C2)OCC)C([2H])([2H])C([2H])([2H])N(CC)C1([2H])[2H]

Oral administration of ZSTK474 ameliorates the progression of adjuvant-induced arthritis (AIA) in rats

ZK-261991 inhibits cellular receptor autophosphorylation in KDR-PAECs with an IC50 of 2 nM

Formula: C13H7F6NO3S

FTI-2153 Catalog No.:M27128-C Smiles: [2H]C1([2H])N(CC(=O)C2=CC(C3NC(=O)C4=C(N=3)C(CCC)=NN4C)=C(C=C2)OCC)C([2H])([2H])C([2H])([2H])N(CC)C1([2H])[2H]FTI 2153 is a potent and highly selective inhibitor of farnesyltransferase (FTase), with an IC50 of 1. 4 nM. FTI 2153 is >3000 fold more potent at blocking H Ras (IC50, 10 nM) than Rap1A processing. Anti cancer activity. Product information CAS Number: 344900 92 1 Molecular Weight: 466. 60 Formula: C25H30N4O3S Chemical Name: methyl (2S) 2 {[5 ({[(1H imidazol 5 yl)methyl]amino}methyl) 2' methyl [1,1' biphenyl] 2 yl]formamido} 4